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| Name: | Ruan Ke | Address: | Room 243, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui, 230027, PR China | Tel: | 0551-63607767 | E-mail: | kruan(AT)ustc.tsg211.com | EDUCATION AND RESEARCH EXPERIENCE 1995-1999 | Peking University
B. S.，Chemistry | 1999-2002 | Peking University
M. S., Physical Chemistry | 2002-2008 | Johns Hopkins University Ph. D., Biophysical Chemistry | 2008-2010 | Pfizer Inc. Global R & D, postdoc | 2010-2011 | CRUK Beatson Institute Drug Discovery Unit, Staff Scientist | 2011-present | University of Science and Technology of China School of Life Sciences, Associate Professor |
RESEARCH INTERESTS Biomolecular NMR spectroscopy, Fragment-based Lead Discovery, Protein Dynamics. |
CURRENT RESEARCH PROJECTS 1. | National R&D project (2016 & 2020) | 2. | NSFC (2019) |
REPRESENTATIVE PUBLICATIONS Xu D.#; Li B.#; Gao J.#; Liu Z.; Niu X.; Nshogoza G.; Zhang J.; Wu J.; Su X.-C.; He W.; Ma R.*; Yang D.*; Ruan K.*; Ligand Proton Pseudocontact Shifts Determined from Paramagnetic Relaxation Dispersion in the Limit of NMR Intermediate Exchange, Journal of Physical Chemistry Letters 9, 3361 (2018). Xu D.; Ma R.; Zhang J.; Liu Z.; Wu B.; Peng J.; Zhai Y.; Gong Q.; Shi Y.; Wu J.; Wu Q.; Zhang Z.*; Ruan K.*; Dynamic Nature of CTCF Tandem 11 Zinc Fingers in Multivalent Recognition of DNA as Revealed by NMR Spectroscopy, Journal of Physical Chemistry Letters 9, 4020 (2018). Gao, Jia#; Liang, E#; Ma, Rongsheng; Li, Fudong; Liu, Yixiang; Liu, Jiuyang; Jiang, Ling; Li, Conggang; Dai, Haiming; Wu, Jihui; Su, Xuncheng; He, Wei; Ruan, Ke*; Fluorine Pseudocontact Shifts Used for Characterizing the Protein-Ligand Interaction Mode in the Limit of NMR Intermediate Exchange, Angew Chem Int Ed Engl, 56): 12982 (2017).
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