EDUCATION AND RESEARCH EXPERIENCE 2003-2007 | University of Science and Technology of China
BS，Applied Physics | 2007-2012 | University of Science and Technology of China
PhD，Structural Biology | 2012-2014 | Washington University in St. Louis Radiology，Postdoctoral Research Associate | 2014-2016 | National Multiple Sclerosis Society Postdoctoral Fellow | 2016-2018 | Washington University in St. Louis Radiology, Instructor | 2019-present | University of Science and Technology of China The First Affiliated Hospital，Professor |
RESEARCH INTERESTS Quantitative magnetic resonance imaging and its clinical applications Molecular imaging method MRI image analysis and processing
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CURRENT RESEARCH PROJECTS 1. | “Targeted MRI based on cyanobacteria gas vesicle”, Joint fund of "USTC New Medicine", PI |
REPRESENTATIVE PUBLICATIONS（按年代倒序排列，粗体突出本人和期刊名） Xiang, B., Wen, J., Lu, H.C., Schmidt, R.E., Yablonskiy, D.A., Cross, A.H., In vivo evolution of biopsy-proven inflammatory demyelination quantified by R2t* mapping. Ann Clin Transl Neurol. 2020. doi: 10.1002/acn3.51052. Xiang, B., J. Wen, A.H. Cross, and D.A. Yablonskiy, Single scan quantitative gradient recalled echo MRI for evaluation of tissue damage in lesions and normal appearing gray and white matter in multiple sclerosis. J Magn Reson Imaging, 2019. 49(2): p. 487-498. Astafiev, S.V., J. Wen, D.L. Brody, A.H. Cross, A.P. Anokhin, K.L. Zinn, M. Corbetta, and D.A. Yablonskiy, A Novel Gradient Echo Plural Contrast Imaging Method Detects Brain Tissue Abnormalities in Patients With TBI Without Evident Anatomical Changes on Clinical MRI: A Pilot Study. Mil Med, 2019. 184(Suppl 1): p. 218-227. Wen, J., M.S. Goyal, S.V. Astafiev, M.E. Raichle, and D.A. Yablonskiy, Genetically defined cellular correlates of the baseline brain MRI signal. Proc Natl Acad Sci U S A, 2018. 115(41): p. E9727-E9736. Wen, J., A.L. Sukstanskii, and D.A. Yablonskiy, Phase-sensitive B1 mapping: Effects of relaxation and RF spoiling. Magn Reson Med, 2018. 80(1): p. 101-111. Cai, B., S.M. Goddu, S. Yaddanapudi, D. Caruthers, J. Wen, C. Noel, S. Mutic, and B. Sun, Normalize the response of EPID in pursuit of linear accelerator dosimetry standardization. J Appl Clin Med Phys, 2018. 19(1): p. 73-85. Adusumilli, G., K. Trinkaus, P. Sun, S. Lancia, J.D. Viox, J. Wen, R.T. Naismith, and A.H. Cross, Intensity ratio to improve black hole assessment in multiple sclerosis. Mult Scler Relat Disord, 2018. 19: p. 140-147. Wen, J., D.A. Yablonskiy, A. Salter, and A.H. Cross, Limbic system damage in MS: MRI assessment and correlations with clinical testing. PLoS One, 2017. 12(11): p. e0187915. Sukstanskii, A.L., J. Wen, A.H. Cross, and D.A. Yablonskiy, Simultaneous multi-angular relaxometry of tissue with MRI (SMART MRI): Theoretical background and proof of concept. Magn Reson Med, 2017. 77(3): p. 1296-1306. Zhao, Y., M.E. Raichle, J. Wen, T.L. Benzinger, A.M. Fagan, J. Hassenstab, A.G. Vlassenko, J. Luo, N.J. Cairns, J.J. Christensen, J.C. Morris, and D.A. Yablonskiy, In vivo detection of microstructural correlates of brain pathology in preclinical and early Alzheimer Disease with magnetic resonance imaging. Neuroimage, 2017. 148: p. 296-304. Cai, B., H. Li, D. Yang, V. Rodriguez, A. Curcuru, Y. Wang, J. Wen, R. Kashani, S. Mutic, and O. Green, Performance of a multi leaf collimator system for MR-guided radiation therapy. Med Phys, 2017. 44(12): p. 6504-6514. Zhao, Y., J. Wen, A.H. Cross, and D.A. Yablonskiy, On the relationship between cellular and hemodynamic properties of the human brain cortex throughout adult lifespan. Neuroimage, 2016. 133: p. 417-429. Wen, J., D.A. Yablonskiy, J. Luo, S. Lancia, C. Hildebolt, and A.H. Cross, Detection and quantification of regional cortical gray matter damage in multiple sclerosis utilizing gradient echo MRI. Neuroimage Clin, 2015. 9: p. 164-75. Mamah, D., J. Wen, J. Luo, X. Ulrich, D.M. Barch, and D. Yablonskiy, Subcomponents of brain T2* relaxation in schizophrenia, bipolar disorder and siblings: A Gradient Echo Plural Contrast Imaging (GEPCI) study. Schizophr Res, 2015. 169(1-3): p. 36-45. Wen, J., A.H. Cross, and D.A. Yablonskiy, On the role of physiological fluctuations in quantitative gradient echo MRI: implications for GEPCI, QSM, and SWI. Magn Reson Med, 2015. 73(1): p. 195-203. Wen, J., Zhou, P., Wu, J., Efficient acquisition of high-resolution 4-D diagonal-suppressed methyl-methyl NOESY for large proteins. J Magn Reson, 2012. 218: p. 128-132. Wen, J., Wu, J., Zhou, P., Sparsely sampled high-resolution 4-D experiments for efficient backbone resonance assignment of disordered proteins. J Magn Reson, 2011. 209(1): p. 94-100.
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